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Chewable tablets for immune defense and upper respiratory health‡


  • Supports first-line immune defense and overall immune health‡
  • Provides support for upper respiratory tract health‡
  • Features EpiCor® Saccharomyces cerevisiae fermentate, nutrients and flavonoids‡
  • Made with high-quality, vegetarian ingredients backed by verifiable science
  • Great-tasting chewable tablet



  • Ages 2 and up
  • Immune function and upper respiratory health support‡

Suggested Use

As a dietary supplement, ages 2-3, take 2 tablets daily, with a meal. Ages 4 and up, take 2 tablets, 1-2 times daily, with a meal.

Science & Research

Verifiable Science

Natural killer cells are part of the body's innate, or first-line, immune response. They respond more quickly than the adaptive immune system comprised of B cells and T cells. Once activated, natural killer cell activity peaks in as quickly as several hours, providing rapid support and wide-range immune defense. EpiCor® is a fermentate of Saccharomyces cerevisiae containing various bioactive metabolites. These nutrient metabolites are produced in a specialized fermentation process and enhance immune cell production. Research suggests that EpiCor® enhances natural killer cell activation, B cell and T cell function, and secretory IgA levels.1 In two randomized, double-blind, placebo-controlled trials, EpiCor® provided statistically significant support for upper respiratory tract health and overall immune health.2,3 A separate open label, in-house trial indicated a strong potential for EpiCor® supplementation to enhance secretory IgA levels after 30 days. In another trial, EpiCor® helped maintain a healthy immune response to environmental factors.4 Elderberry extract provides anthocyanins, flavonoids, and other polyphenols that support immune function. Studies have shown statistically significant immune support in both children and adults.5,6 Preliminary research suggests quercetin helps to moderate the release of immune mediators, including cytokines and histamine.7,8 Zinc and vitamin C help to promote immune defense by supporting immune cell proliferation, activation and function, as well as healthy antioxidant enzyme function.9‡



Jensen GS, et al. J Med Food. 2015 Mar;18(3):378-84.

Moyad MA, et al. Urol Nurs. 2008 Feb;28(1):50-5.

Talbott SM, et al. J Am Coll Nutr. 2012 Aug;31(4):295-300.

Moyad MA, et al. Adv Ther. 2009 Aug;26(8):795-804.

Zakay-Rones Z, et al. J Altern Complement Med. 1995 Winter;1(4):361-9.

Tiralongo E, Wee SS, Lea RA. Nutrients. 2016 Mar 24;8(4). pii: E182.

Kumar P, et al. Int J Exp Pathol. 2003 Jun;84(3):127-33.

Weng Z, et al. PLoS One. 2012;7(3):e33805.

Wintergerst ES, et al. Ann Nutr Metab. 2006;50(2):85-94.


‡These statements have not been evaluated by the Food & Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

PureDefense Chewables

SKU: 0766298015910
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