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Supports dopamine production and maintains healthy reuptake for daily mental function and sharpness‡


  • Promotes the production of dopamine to support daily cognitive function and performance on mental tasks‡
  • Supports the stability of dopamine and maintains healthy dopamine reuptake‡
  • Protects neuronal health and function‡
  • Supports mood‡
  • Includes folate as Metafolin® 5- methyltetrahydrofolate (L-5-MTHF), the universally metabolized and biologically active form of folate
  • Part of the PureSYNAPSE;&trade product line
  • Made with high-quality vegetarian ingredients backed by verifiable science



  • Ages 18 and up
  • Cognitive support‡
  • Positive mood support‡

Suggested Use

As a dietary supplement, take 3 capsules, 1-2 times daily, with low protein foods.

Science & Research

Verifiable Science

DopaPlus promotes the production of dopamine to support daily cognitive function and performance on mental tasks. This formula provides the dopamine precursors L-tyrosine and L-DOPA (from Mucuna pruriens). In a randomized, controlled, double-blind, crossover trial, Mucuna pruriens supplementation promoted L-DOPA plasma concentrations.1 The cofactors vitamin B6 , folate (as Metafolin® L-5-MTHF) and zinc support dopamine production.2 Studies show that supporting optimal serum levels of these nutrients promote positive mood.3 Rhodiola and green tea polyphenols promote the stability of dopamine and maintain healthy dopamine reuptake.4 Grape seed proanthocyanidins support cognitive function and mental sharpness.5 Green tea and grape seed polyphenols help to maintain neuronal health and function.6‡



Katzenschlager R, et al. J Neurol NeurosurgPsychiatry 2004;75:1672-1677.

Passeri M, et al. Aging (Milano). 1993 Feb;5(1):63-71.

Ranjbar E, et al. Nutr Neurosci. 2014 Feb;17(2):65-71.

Darbinyan V, et al. Nord J Psychiatry.2007;61(6):503.

Asha Devi S, et al. Exp Gerontol. 2011 Nov;46(11):958-64.

Niu K, et al. Am J Clin Nutr. 2009 Dec;90(6):1615-22


‡These statements have not been evaluated by the Food & Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.


SKU: 0766298014555
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